Airway Tmps Oral bronchodilator and antibacterial for the treatment of respiratory diseases in horses.

ACTIVE CONSTITUENTS

Clenbuterol Hydrochloride         21.44ug/g

Sulfadiazine                            335mg/g

Trimethoprim                           67mg/g

 

PACK SIZE

500g

 

PHARMACOLOGY

Airway Tmps Oral Powder is formulated for the treatment of respiratory disease in horses  caused by organisms susceptible to trimethoprim and sulfadiazine combination therapy. It is for treatment of respiratory conditions characterised by restriction or obstruction of airways, including bronchospasm and obstruction resulting from bacterial and viral infection, bronchitis and bronchopneumonia. Airway Tmps Oral Powder is indicated whenever bronchodilation and antibacterial protection is desirable. Clenbuterol is a sympathomimetic amine that blocks beta2-receptor sites in the body, including those in lungs and uterus. This allows for maximum  bronchodilation with improved pulmonary ventilation and mucus clearance without significant effects on the heart and blood vessels.

INDICATIONS

For the treatment of respiratory disease in horses caused by organisms susceptible to a trimethoprim/sulfadiazine combination. Treatment of respiratory conditions characterised by restriction of the airways, including bronchospasm and obstruction resulting from bacterial and viral infection, bronchitis and bronchopneumonia. Indicated where bronchodilation and antibacterial protection is desirable.

CONTRAINDICATIONS

Airway Tmps Oral Powder will potentiate the action of corticosteroids, and antagonise the effects of prostaglandin F2alpha and oxytocin. Beta adrenergic agents adversely affect the action of  Airway Tmps. Concurrent treatment of horses with these medications is not recommended.

Airway Tmps Oral Powder should not be used in horses during the last 14 days of gestation, as  uterine contractions may be prevented.

ORAL ADMINISTRATION IN HORSES

One level scoop (9g) orally per 250kg bodyweight to be added to feed twice daily for 6 to 10 days. Twice daily dosing is recommended to maintain therapeutic levels of active drugs in all situations.

TIPS

Clenbuterol is a bronchodilator with minimal effect on the cardiovascular system. Clenbuterol also has a stabilising effect on mast cells, preventing the release of histamine, serotonin and  bradykinin, therefore has a beneficial effect to clear mucociliary discharge .The spectrum of  bacteria sensitive to this antibiotic combination includes; Staphylococci, Streptococci,  Fusobacterium, Eneterobacter, Corynebacterium (excluding Rhodococcus equi), Salmonella, Shigella, Klebsiella, Powderurella, Haemophilus, Proteus spp and most E.coli, some Brucella and Nocardia spp. Most Pseudomonas spp are insensitive. Bacterial culture and sensitivity  testing should be carried out in cases of non-responsive or chronic infection.

MEAT WITHHOLDING PERIOD

DO NOT USE in horses that may be slaughtered for human consumption.

RACING/EVENT WITHHOLDING PERIOD

If used in performance animals, the regulations of the relevant authorities regarding medication should be observed.

HANDLING PRECAUTIONS

May be harmful if swallowed. May cause skin irritation. Repeated exposure may cause skin allergy. May cause eye irritation. Avoid inhalation. May cause respiratory sensitisation. Trimethoprim possibly may affect bone.

Handle with care.

FIRST AID

If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131126 or in New Zealand 0800 764 766. If skin or hair contact occurs flush with running water. If splashed in eyes wash out immediately with water. If inhaled remove patient to fresh air.

DISPOSAL

Dispose of empty container by wrapping with paper and putting in garbage.

STORAGE

Store below 30°C (Room temperature). Protect from light.

REGISTRATION

APVMA Approval No. 61474/500/0807 (Australia)

ACVM  A10158 (New Zealand)

 

 

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