Airway Tmps Oral bronchodilator and antibacterial for the treatment of respiratory diseases.

ACTIVE CONSTITUENTS

Clenbuterol Hydrochloride         21.44ug/g

Sulfadiazine                            335mg/g

Trimethoprim                           67mg/g

 

PACK SIZE

500g jar

 

INDICATIONS

For the treatment of respiratory disease in horses caused by organisms susceptible to an antibiotic trimethoprim/sulfadiazine combination. Treatment of respiratory conditions characterised by restriction of the airways, including bronchospasm and obstruction resulting from bacterial and viral infection, bronchitis and bronchopneumonia. Indicated where bronchodilation and antibacterial protection is desirable..

PHARMACOLOGY

Airway Tmps Oral Powder is formulated for the treatment of respiratory disease in horses caused by organisms susceptible to the trimethoprim/sulfadiazine antibiotic combination. These include; Staphylococci, Streptococci, Fusobacterium, Eneterobacter, Corynebacterium (excluding Rhodococcus equi), Salmonella, Shigella, Klebsiella, Pasteurella, Haemophilus, Proteus spp and most E.coli, some Brucella and Nocardia spp. Most Pseudomonas spp are insensitive.

Clenbuterol is a bronchodilator with minimal effect on the cardiovascular system. Clenbuterol also has a stabilising effect on mast cells, preventing the release of histamine, serotonin and bradykinin and therefore has a beneficial effect to clear mucociliary discharge.

CONTRAINDICATIONS

Airway Tmps Oral Powder will potentiate the action of corticosteroids and antagonise the effects of prostaglandin F2 and oxytocin. Beta adrenergic agents adversely affect the action of Airway Tmps. Concurrent treatment of horses with these medications is not recommended. Airway Tmps Oral Powder should not be used in horses during the last 14 days of gestation, as uterine contractions may be prevented.

ORAL ADMINISTRATION IN HORSES

Whenever possible, bacterial culture and sensitivity testing should be carried out prior to initiating treatment with Airway Tmps and in cases of non-responsive or chronic infection.

Administer on damp food with honey or molasses to avoid sifting of powder. Alternatively, Airways Tmps may be made up as a paste with molasses, honey or Karo Syrup and administered over the back of the tongue. One level scoop (9g) orally per 250kg bodyweight to be added to feed twice daily for 6 to 10 days. Twice daily dosing is recommended to maintain therapeutic levels of active drugs in all situations..

HANDLING PRECAUTIONS

May be harmful if swallowed. May cause skin irritation. Repeated exposure may cause skin allergy. May cause eye irritation. Avoid inhalation. May cause respiratory sensitisation. Trimethoprim possibly may affect bone.

MEAT WITHHOLDING PERIOD

Nil.

RACING/EVENT WITHHOLDING PERIOD

If used in performance animals, the regulations of the relevant authorities regarding medication should be observed.

FIRST AID

If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131126 or in New Zealand 0800 764 766. If skin or hair contact occurs flush with running water. If splashed in eyes wash out immediately with water. If inhaled remove patient to fresh air.

DISPOSAL

Dispose of empty container by wrapping with paper and putting in garbage.

STORAGE

Store below 30°C (Room temperature). Protect from light.

REGISTRATION

APVMA Approval No. 61474/500/0807 (Australia)

ACVM No. A10158 (New Zealand)

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