30mL single vial
Altrenogest acts similarly to the natural hormone, progesterone, by suppressing the normal oestrus cycle and preventing signs of heat and ovulation. Mares return to heat and release natural hormones again once treatment stops. Treatment with altrenogest makes it possible to regulate the breeding of mares.
Ovu-Mate injection may be used in fillies and mares to:
• Delay the onset of oestrus
• Suppress oestrous behaviour.
Pharmacokinetic data from mares treated with Ovu-Mate, have shown blood levels of altrenogest are maintained for 5 days following administration of the injection. Studies have been conducted to support suppression of behavioural signs of oestrus in cycling mares for 7 days following administration of Altrenogest Injection.
Although weekly Ovu-Mate injections have been used for the maintenance of pregnancy in habitually aborting mares, its use in the maintenance of pregnancy has not yet been established in clinical trials.
This product is contraindicated for use in stallions and geldings. Ovu-Mate use in pregnant mares has not been established.
There is evidence that when progestagens are administered to rats during the embryonic stage of pregnancy at doses higher than the recommended equine dose, foetal abnormalities (specifically masculinisation of female genitalia) can result. If used in performance animals, the regulations of the relevant authorities regarding medication should be observed.
DOSAGE AND ADMINISTRATION
3mL per 500kg bodyweight (0.3mg/kg) by intramuscular injection once every 5-7 days as required to suppress signs of oestrus. The dose rate should be extrapolated according to bodyweight if treating lighter or heavier horses.
Care should be taken to avoid contact between the solution and women of child bearing age. Product is harmful if absorbed by skin contact or inhaled or swallowed. Avoid contact with eyes and skin. Do not inhale. When using the product wear rubber gloves. After use and before eating, drinking or smoking, wash hands, arms and face thoroughly with soap and water. After each day’s use wash gloves.
Additional User Safety: Warning: Suspected of damaging infertility or the unborn child. Women who are pregnant or suspected of being pregnant should not handle the product. Women of childbearing age should handle the product with extreme care. Not to be handled by persons with known or suspected progesterone dependent tumours or thromboembolic disorders.
MEAT WITHHOLDING PERIOD
NOT TO BE USED in horses that may be used for human consumption.
RACING/EVENT WITHHOLDING PERIOD
If used in performance animals, the regulations of the relevant authorities regarding medication should be observed.
If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131126 or in New Zealand 0800 764 766.
Dispose of empty container by wrapping with paper and putting in garbage.
Store below 25°C (Air Conditioning). Store in an upright position. Protect from light. Discard unused portion within 28 days of first broaching of vial..
APVMA Approval No. 83216/107741 (Australia)
ACVM No. A11475 (New Zealand)