Veterinary Medicines

Sed-Ace As an aid in quieting excitable, nervous, unruly or hard to handle horses.


Each mL contains Acepromazine Maleate 12mg


30mL Adjustable dose syringe


As an aid in quieting excitable, nervous, unruly or hard to handle horses.


Orally administered acepromazine maleate to provide a dose-dependent tranquiliser, relaxant and sedative effects in horses. SED-Ace Oral Gel provides a safe, convenient and effective method of tranquilising and sedating horses. Acepromazine maleate mediates hypotensive, hypothermic and antispasmodic actions. It has little, if any, analgesic effect, so that painful procedures must be avoided, particularly where animals are known to have unpredictable temperaments.

Tranquilising Action - Low doses of oral acepromazine maleate promote a mild tranquilising effect, useful as an aid in quietening excitable, nervous and hard-to-handle horses. It can provide a beneficial “calming” effect during handling, transport and confinement. It reduces excitability, whilst retaining co-ordination and awareness of environment.

Examples of Use of SED-Ace Oral Gel

 - An aid in training horses.

 - To calm nervous horses and reduce stress (alleviates the use of whips, hobbles and twitches).

 - In minor surgical procedures in which an anaesthetic is not required.

 - As a preanaesthetic, to augment action and permit smooth induction and recovery.

 - In non surgical procedures such as shoeing and dentistry.

 - Handling mares during breeding.

 - Horses that have wounds which cannot heal due to constant irritation (biting, licking etc.)

 - After major surgery to reduce straining.

 - Useful aid in the treatment of colic and tetanus.

 - To calm horses during transport.


Whilst SED-Ace Oral Gel is not intended for routine use as an anaesthetic premedication, situations may arise where general anaesthesia is required in 4-6 hours following use of the product. Care should be taken to reduce the induction dose of other premedications and anaesthetic agents, particularly parenteral barbiturates, so as to avoid potentiation and additive depressant effects.


Contraindicated for use in breeding stallions. Paralysis of the retractor penis muscle has been associated with the use of parenterally administered acepromazine maleate in horses.

Acepromazine maleate is hypotensive, and must be administered with caution to animals exhibiting symptoms of debilitation, congestive heart failure, sympathetic blockage, hypovolaemia or shock. Tranquilisers are additive to the functions of other depressants, and will potentiate general anaesthesia. Do not use this product in conjunction with organophosphates and/or procaine hydrochloride, as it may enhance activity and potential toxicity. Adrenaline (epinephrine) is contra-indicated in the treatment of acute hypotension produced by over-dosage of acepromazine maleate, since further depression of systemic blood pressure can result. Other pressoramines, such as noradrenaline (norepinephrine) or neosynephrine should be administered to reverse hypotensive effects.


To be given orally to horses. The required dosage of SED-Ace Oral Gel may vary depending on the individual temperament of the animal. When administered to male horses (geldings or stallions), use the lowest dose recommended to produce the required effect.

Horses 4-10 mL per 450 kg bodyweight 0.13 mg to 0.26 per kg bodyweight.

The tranquilisation effect may be more pronounced if feed and water intake is limited during a period of five hours before dosing. On an empty stomach, tranquilisation effect will be apparent in horses within 20-40 minutes, and with duration of up to 12 hours. On a full stomach, full tranquilisation effect will be apparent within 40-60 minutes or longer, with duration of 12 hours.

For best results, avoid excitement or stimulation of the animal prior to administration.

During sedation, horses will normally retain visual and auditory acuity, so that loud sounds and rapid movements should be avoided. Exceeding the recommended dosage will not necessarily intensify the effect of this product. The following administration technique will ensure accurate dosage with minimal wastage of paste. Remove cap from nozzle. Turn ring to required dose setting which should be on the left of the ring. Insert the nozzle into the animal’s empty mouth. Direct towards back of tongue, and depress plunger to deposit paste. Lift animal’s chin and hold mouth closed for a few seconds to ensure that full dose is swallowed. Replace cap on nozzle after use.


28 Days


If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131 126.


Dispose of empty container by wrapping in paper and placing in garbage.


Store below 30oC (room temperature).


ACVM No. A011152 (New Zealand)



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