Sedator Injection For mild to heavy sedation and for analgesia in cattle and horses. 
For control of pain in uncomplicated colic in horses.




5mL Single vial


Sedator is a dose controlled sedative and analgesic. It may be used to facilitate examinations, x-rays, minor surgical operations, transport etc. It may be used to control pain including that of the uncomplicated equine colic case.

Sedator has a role in providing prolonged analgesia (upto 12 hours) in horses for example with an accident case.

For analgesia in COLIC in horses the recommended dose is 20-40μg/kg BW (0.2-0.4mL/kg BW) until diagnosis is confirmed.

“Sedator is a sedative and analgesic that may be used to facilitate:

• Examinations e.g. Endoscopy, rectal palpation, gynaecological examinations and x-rays.

• Minor surgical procedures e.g. Treatment of wounds, removal of skin tumours, hoof care and castration.

• Treatment and medication e.g. use of nasogastric tube and shoeing.

In painful procedures detomidine should be used in combination with an analgesic or a local anaesthetic”.


As the safety of Sedator during pregnancy and lactation has not been adequately documented, its use is not recommended during the last month of pregnancy.

Intravenous potentiated sulphonamides are contraindicated in sedated or anaesthetised horses as potentially fatal dysrhythmias may occur.


Sedator may cause penile relaxation. Use with caution on male animals, particularly during breeding.

Clinicians should anticipate the occasional tendency of the animal’s head to drop under the influence of Sedator and the subject should be accommodated appropriately.

Immediately following administration there may be a tendency to stagger, particularly if high dose rates are employed.

Fasting prior to Sedator sedation is not necessary. The animal should not be fed until the effect of the drug has worn off.

The safe handling of horses and cattle can be improved with Sedator. Although the animal is easy to handle under Sedator sedation, normal restricting methods are recommended. Local anaesthetics can be used when required for painful procedures, particularly surgery, as the duration of analgesia from Sedator may not equate with the duration of sedation.

“A risk/benefit assessment should be undertaken by a veterinarian before using this product in animals suffering from cardiac disease (with pre-existing bradycardia and risk of atrioventricular block), respiratory, liver or renal insufficiencies or shock”.

“If cattle lie down avoid ruminal bloat and aspiration of feed or saliva by maintaining in sternal recumbency during and following treatment with head and neck lowered”.


The symptoms may be relieved by atropine or specific alpha-2 antagonist.


Harmful side effects have not been observed. Sympathomimetic properties, particularly at higher doses, may include piloerection, sweating, diuresis and occasional slight tremors.


Horses and Cattle: Administration is by slow intravenous or the intramuscular route.

The effects begin soon after IV administration.

Tissue tolerance to Sedator is good.

For analgesia in COLIC until diagnosis is confirmed, recommended dose is 20 – 40 μg/kg BW (0.2 – 0.4 mL/100 kg BW).

The full analgesic effect is established by 5 – 15 minutes following administration.

If the desired level of sedation is not achieved following administration of a low dose, a further, additive, dose may be given.

When using Sedator extra fuss should be avoided.


It is an offence for users of this product to cause residues exceeding the relevant MRL in the New Zealand (Maximum Residues of Agricultural Compounds) Food Standards.

Cattle: Meat: Nil; Milk: Nil

Horses: Meat: Nil


Detomidine (in Sedator) is a centrally acting alpha-2 adrenergic agonist, similar in its pharmacology to clonidine. Sedator is a potent preparation and any accidental spillage etc should be promptly washed off. Accidental administration to humans may produce hypertension of variable duration which may be followed by hypotension. First stage aid should include careful monitoring of the blood pressure with administration of phentolamine if dangerous levels of hypertension develop. Hypotension should be treated with fluid replacements and other supportive measures.


If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131126, New Zealand 0800 764 766.


Dispose of empty containers, outer packaging or expired product by wrapping with paper and putting in garbage.


Store below 25°C (air conditioning). Protect from light.

In-use shelf life: 11 weeks from initial broaching.



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