Ulcers

Effect of gastric ulceration on physiologic responses to exercise in horses. Am J Vet Res 2009;70:787–795. Nieto JE, Snyder JR, Vatistas NJ, Jones JH.

Rethinking equine gastric ulcer syndrome: Part 2 – Equine squamous gastric ulcer syndrome (ESGUS).. 
Sykes, B.W. and Jokisalo, J.M., 2015. Equine Veterinary Education, 27(5), pp.264-268.

The effects of dose and diet on the pharmacodynamics of omeprazole in the horse.
Sykes, B.W., Underwood, C., Greer, R., McGowan, C.M. and Mills, P.C., 2016. Equine Veterinary Journal.

Rethinking equine gastric ulcer syndrome: Part 3–Equine glandular gastric ulcer syndrome (EGGUS).
Sykes, B. and Jokisalo, J.M., 2015. Equine Veterinary Education, 27(7), pp.372-375.

Rethinking equine gastric ulcer syndrome: Part 1–Terminology, clinical signs and diagnosis.
Sykes, B.W. and Jokisalo, J.M., 2014. Equine Veterinary Education, 26(10), pp.543-547.

Administration of trimethoprim-sulphadimidine does not improve healing of glandular gastric ulceration in horses receiving omeprazole: a randomised, blinded, clinical study.
Sykes, B.W., Sykes, K.M. and Hallowell, G.D., 2014. BMC veterinary research, 10(1), p.1.

Poor performance associated with equine gastric ulceration syndrome in four Thoroughbred racehorses.
Franklin, S.H., Brazil, T.J. and Allen, K.J., 2008. Equine Veterinary Education, 20(3), pp.119-124.

Gastric juice pH measurement in horses: Three‐quarters of a century of history!.
Andrews, F.M., 2015. Equine Veterinary Education, 27(12), pp.633-636.

Pharmacokinetics, metabolism and interactions of acid pump inhibitors.
Andersson, T., 1996. Clinical pharmacokinetics, 31(1), pp.9-28.

Pharmacokinetics and bioavailability of omeprazole after single and repeated oral administration in healthy subjects.
Andersson, T., Andren, K., Cederberg, C., Lagerstrom, P.O., Lundborg, P. and Skanberg, I., 1990. British journal of clinical pharmacology, 29(5), pp.557-563.

Equine gastric ulcer syndrome in adult horses: a review.
Bell, R.J.W., Mogg, T.D. and Kingston, J.K., 2007. New Zealand Veterinary Journal, 55(1), pp.1-12.

Pharmacology and toxicology of omeprazole with special reference to the effects on the gastric mucosa.
Carlsson, E., Larsson, H., Mattsson, H., Ryberg, B. and Sundell, G., 1986. Scandinavian Journal of Gastroenterology,21(sup118), pp.31-38.

The structure of Omeprazole in the solid state: a 13 C and 15 N NMR/CPMAS study.
Claramunt, R.M., López, C. and Elguero, J., 2006. Arkivoc,5, p.11.

Effect of omeprazole paste on gastric acid secretion in horses.
Daurio, C.P., Holste, J.E., Andrews, F.M., Merritt, A.M., Blackford, J.T., Dolz, F. and Thompson, D.R., 1999. Equine Veterinary Journal, 31(S29), pp.59-62.

Efficacy of a paste formulation of omeprazole for the treatment of naturally occurring gastric ulcers in training standardbred racehorses in Canada.
Doucet, M.Y., Vrins, A.A., Dionne, R., Alva, R. and Ericsson, G., 2003. The Canadian Veterinary Journal, 44(7), p.581.

The effect of 90 days treatment with Omeprazole on 24 hour plasma gastrin profiles in female Wistar rats.
Earl, L.K. and Man, K.L., 1990. Biochemical pharmacology, 39(3), pp.618-622.

Recommendations for the diagnosis and treatment of equine gastric ulcer syndrome (EGUS).
Andrews, F., Bernard, W., Byars, D., Cohen, N., Divers, T., MacAllister, C., McGladdery, A., Merritt, A., Murray, M., Orsini, J. and Snyder, J., 1999. Equine Vet Educ, 1(2), pp.122-34.

Toxicological studies on omeprazole.
Ekman, L., Hansson, E., Havu, N., Carlsson, E. and Lundberg, C., 2009. Scandinavian Journal of Gastroenterology.

Omeprazole Disposition in Children following Single‐Dose Administration.
Kearns, G.L., Andersson, T., James, L.P., Gaedigk, A., Kraynak, R.A., Abdel‐Rahman, S.M., Ramabadran, K. and Anker, J.N., 2003. The Journal of Clinical Pharmacology, 43(8), pp.840-848.

Evaluation of omeprazole genotoxicity in a battery of in vitro and in vivo assays.
Martelli, A., Mattioli, F., Mereto, E., Campart, G.B., Sini, D., Bergamaschi, G. and Brambilla, G., 1998. Toxicology, 130(1), pp.29-41.

Efficacy of omeprazole paste for prevention of gastric ulcers in horses in race training.
McClure, S.R., White, G.W., Sifferman, R.L., Bernard, W., Doucet, M.Y., Vrins, A., Holste, J.E., Fleishman, C., Alva, R. and Cramer, L.G., 2005. Journal of the American Veterinary Medical Association, 226(10), pp.1681-1684.

Comparison of paste and suspension formulations of omeprazole in the healing of gastric ulcers in racehorses in active training. Nieto, J.E., Spier, S., Pipers, F.S., Stanley, S., Aleman, M.R., Smith, D.C. and Snyder, J.R., 2002. Journal of the American Veterinary Medical Association, 221(8), pp.1139-1143.

Pharmacokinetics and metabolism of omeprazole in animals and man - an overview.
Regårdh, C.G., Gabrielsson, M., Hoffman, K.J., Löfberg, I. and Skånberg, I., 1985. Scandinavian Journal of Gastroenterology, 20(sup108), pp.79-94.

Effects of misoprostol and omeprazole on basal gastric pH and free acid content in horses.
Sangiah, S., MacAllister, C.C. and Amouzadeh, H.R., 1989. Research in veterinary science, 47(3), pp.350-354.

Pharmacokinetics and bioavailability of five commercially available formulations of omeprazole.
Sykes, B.W., Underwood, C., McGowan, C. and Mills, P., 2015. J Vet Pharm Ther, pp.1-6.

Prostaglandins, NSAIDs, and gastric mucosal protection: why doesn't the stomach digest itself?.
Wallace, J.L., 2008. Physiological reviews, 88(4), pp.1547-1565.

Design and in vitro/in vivo evaluation of multi-layer film coated pellets for omeprazole.
He, W., Fan, L.F., Du, Q., Xiang, B., Li, C.L., Bai, M., Chang, Y.Z. and Cao, D.Y., 2009. Chemical and Pharmaceutical Bulletin, 57(2), pp.122-128.

Inhibition of gastric (H++ K+)-ATPase by the substituted benzimidazole, picoprazole.
Wallmark, B., Sachs, G., Mårdh, S. and Fellenius, E., 1983. Biochimica et Biophysica Acta (BBA)-Biomembranes, 728(1), pp.31-38.

Effects of short-term light to heavy exercise on gastric ulcer development in horses and efficacy of omeprazole paste in preventing gastric ulceration.
White, G., McClure, S.R., Sifferman, R., Holste, J.E., Fleishman, C., Murray, M.J. and Cramer, L.G., 2007. Journal of the American Veterinary Medical Association, 230(11), pp.1680-1682.

Gastric ulcers in horses.
Andrews, F.M., Buchanan, B.R., Elliot, S.B., Clariday, N.A. and Edwards, L.H., 2005. Journal of Animal Science,83(13_suppl), pp.E18-E21.

Inhibition of volume‐activated chloride currents in endothelial cells by chromones.
Heinke, S., Szücs, G., Norris, A., Droogmans, G. and Nilius, B., 1995. British journal of pharmacology, 115(8), pp.1393-1398.

E3710, a new proton pump inhibitor, with a long-lasting inhibitory effect on gastric acid secretion.
Kodama, K., Fujisaki, H., Kubota, A., Kato, H., Hirota, K., Kuramochi, H., Murota, M., Tabata, Y., Ueda, M., Harada, H. and Kawahara, T., 2010. Journal of Pharmacology and Experimental Therapeutics,334(2), pp.395-401.

Effect of omeprazole paste on intragastric pH in clinically normal neonatal foals.
Sanchez, L.C., Murray, M.J. and Merritt, A.M., 2004. American journal of veterinary research, 65(8), pp.1039-1041.

Coated pellets for omeprazole Design and in vitro/in vivo evaluation of multi-layer film.
He, W., Fan, L.F., Du, Q., Xiang, B., Li, C.L., Bai, M., Chang, Y.Z. and Cao, D.Y., 2009. Chemical and Pharmaceutical Bulletin, 57(2), pp.122-128.

Nutritional management of gastric ulceration. EQUINE VETERINARY EDUCATION 45
Equine vet. Educ. (2017) 29 (1) 45-55, doi: 10.1111/eve.12495, F. M. Andrews†*, C. Larson‡ and P. Harris§

 

 

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